Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Do We Really Care About Our Children's School Safety? The Proof Is in the Pudding.

WMJ : official publication of the State Medical Society of Wisconsin·2026
Same author

Long-term lung function decline from chronic workplace exposure in roadside vendors of Peshawar, Pakistan.

Journal of public health research·2026
Same author

Diagnostic Accuracy of Cerebroplacental Ratio in Predicting Adverse Perinatal Outcomes in Pregnancies with Intrauterine Growth Restriction.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same author

Can You Properly Manage Delusional Parasitosis?

Innovations in clinical neuroscience·2025
Same author

Resurgence of polio and the path to eradication.

Tropical medicine & international health : TM & IH·2025
Same author

Babesiosis - An Unseen Epidemic.

WMJ : official publication of the State Medical Society of Wisconsin·2025
Same journal

Response to "Burnout and Ethical Awareness in Mental Health Professionals: A Correlational Study".

Innovations in clinical neuroscience·2026
Same journal

Social Media Use and Technology Use in Patients with Intellectual and Developmental Disabilities.

Innovations in clinical neuroscience·2026
Same journal

Post-SSRI Sexual Dysfunction: Challenges and Treatment Approaches.

Innovations in clinical neuroscience·2026
Same journal

An Overview of Medical Errors in Psychiatry, Part 1: Introduction.

Innovations in clinical neuroscience·2026
Same journal

Responding to Correspondence on "Burnout and Ethical Awareness in Mental Health Professionals: A Correlational Study".

Innovations in clinical neuroscience·2026
Same journal

"AI Literacy" is a Deflection of Responsibility.

Innovations in clinical neuroscience·2026
See all related articles

Related Experiment Video

Updated: May 25, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Opsoclonus myoclonus.

Jonathan R Scarff1, Bushra Iftikhar, Aniket Tatugade

  • 1University of Louisville School of Medicine, Department of Psychiatry and Behavioral Sciences, Louisville, Kentucky, USA.

Innovations in Clinical Neuroscience
|January 17, 2012
PubMed
Summary
This summary is machine-generated.

Opsoclonus myoclonus, a rare autoimmune disorder causing cerebellar degeneration, is often linked to cancer. Treatment involves addressing the cause and using anti-inflammatory therapies.

Keywords:
Opsoclonus myoclonusautoimmunecerebellar signscerebellar toxicitydancing eyesdancing feet syndromeopsoclonusparaneoplastic

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
06:09

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

Related Experiment Videos

Last Updated: May 25, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
06:09

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

Area of Science:

  • Neurology
  • Immunology
  • Oncology

Background:

  • Opsoclonus myoclonus is a rare autoimmune disorder.
  • It is characterized by cerebellar degeneration and often presents as a paraneoplastic syndrome.
  • Commonly known as "dancing eyes, dancing feet syndrome," it involves rapid, involuntary eye movements and ataxia.

Purpose of the Study:

  • To summarize the key features of opsoclonus myoclonus.
  • To discuss its various etiologies, including paraneoplastic, infectious, metabolic, and idiopathic causes.
  • To outline current treatment strategies and prognostic factors.

Main Methods:

  • Literature review of opsoclonus myoclonus cases.
  • Analysis of clinical presentation, diagnostic criteria, and treatment outcomes.
  • Focus on pediatric (neuroblastoma-associated) and adult cases.

Main Results:

  • Half of opsoclonus myoclonus cases occur in children with neuroblastoma.
  • Adult etiologies are diverse, including neoplastic, infectious, metabolic, or idiopathic.
  • Antibody-mediated neuronal damage is a key pathogenic mechanism.

Conclusions:

  • Treatment requires addressing the underlying etiology and implementing anti-inflammatory therapies.
  • Children with neuroblastoma-associated opsoclonus myoclonus may have long-term neurological deficits.
  • Adults with idiopathic or infectious causes generally have a better prognosis than those with neoplastic origins.