Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 25, 2026

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
08:50

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation

Published on: August 20, 2019

Phase 2 study examining magnesium-dependent tinnitus.

Michael J Cevette1, David M Barrs, Alpen Patel

  • 1Department of Otolaryngology, Mayo Clinis, Scottsdale, AZ, USA. Cevette.michael@mayo.edu

The International Tinnitus Journal
|January 18, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hearing Through the Patient's Ears: Hearing Simulation for Counseling and Education.

Audiology research·2026
Same author

Using Galvanic Vestibular Stimulation to Null and Enhance Real-World Motion Perception.

Aerospace medicine and human performance·2026
Same author

AI-Driven Prediction of Possible Mild Cognitive Impairment Using the Oculo-Cognitive Addition Test (OCAT).

Brain sciences·2026
Same author

Use of Echocardiography Under Hypoxic Stress Without Exercise to Assess Right to Left Shunting.

Journal of cardiovascular development and disease·2025
Same author

Psychometric Properties and Interpretability of PRO-CTCAE<sup>®</sup> Average Composite Scores as a Summary Metric of Symptomatic Adverse Event Burden.

Cancers·2025
Same author

Methods for implementing and reporting the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events to measure patient-reported adverse events in cancer clinical trials.

Cancer·2025
Same journal

Recurrent Cholesteatoma: Why it occurs?

The international tinnitus journal·2024
Same journal

The Labyrinthine Journey: Unveiling Obstacles in addressing Mental Health Challenges in Prisons and its Confluence with Medico-Legal and Pharmacological Perspectives.

The international tinnitus journal·2024
Same journal

Pulsed Radiofrequency of the Auriculotemporal Nerve to Reduce the Intensity of Tinnitus.

The international tinnitus journal·2024
Same journal

COVID-19 Vaccination Effects on Tinnitus and Hyperacusis: Longitudinal Case study.

The international tinnitus journal·2024
Same journal

Gerstmann Syndrome Case-Control Study: Correlation between Brain Lesions & Functional Disability.

The international tinnitus journal·2024
Same journal

Surgical Option for External Auditory Canal Cholesteatoma: A Case Report.

The international tinnitus journal·2024
See all related articles

Magnesium supplementation may reduce tinnitus severity and handicap. This study found significant decreases in tinnitus distress and handicap scores after 3 months of daily magnesium intake.

Area of Science:

  • Otolaryngology
  • Nutritional Neuroscience
  • Clinical Audiology

Background:

  • Emerging research suggests magnesium may alleviate noise-induced and idiopathic sensorineural hearing loss.
  • Epidemiological data reveal widespread magnesium deficiency in the American population.

Purpose of the Study:

  • To investigate the efficacy of supplemental magnesium in reducing tinnitus severity.
  • To assess the impact of magnesium on patient-reported tinnitus distress and handicap.

Main Methods:

  • Open-label, single-arm study involving 26 patients with moderate to very severe tinnitus.
  • Daily oral magnesium (532 mg) supplementation for 3 months.
  • Tinnitus severity assessed via Tinnitus Distress Rating (TDR) scale and Tinnitus Handicap Inventory (THI) converted to Tinnitus Severity Scale (TSS) grades.

More Related Videos

Understanding the Effects of Non&#45;Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV
04:59

Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV

Published on: January 19, 2024

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Meni&#232;re's Disease Ears and Normal Hearing Ears
10:27

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears

Published on: February 21, 2018

Related Experiment Videos

Last Updated: May 25, 2026

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation
08:50

Brain State-dependent Brain Stimulation with Real-time Electroencephalography-Triggered Transcranial Magnetic Stimulation

Published on: August 20, 2019

Understanding the Effects of Non&#45;Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV
04:59

Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation on EEG and HRV

Published on: January 19, 2024

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Meni&#232;re's Disease Ears and Normal Hearing Ears
10:27

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears

Published on: February 21, 2018

Main Results:

  • A significant decrease in tinnitus handicap (THI/TSS) was observed in subjects with slight or greater impairment (P=.03).
  • Patients reported a significant reduction in tinnitus severity post-intervention (P=.008).
  • Nineteen of 26 enrolled patients completed the study.

Conclusions:

  • Magnesium supplementation shows potential benefits for managing tinnitus-related handicap.
  • The findings suggest magnesium may positively influence the perception of tinnitus.