Related Experiment Video
Updated: May 25, 2026

08:09
Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
Published on: November 16, 2015
Hypertrophied tonsils impair velopharyngeal function after palatoplasty
1Department of Otolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt. mosabeez@yahoo.com
The Laryngoscope
|January 19, 2012
Summary
Tonsillectomy improved velopharyngeal function and speech resonance in children with repaired cleft palate and tonsillar hypertrophy. This intervention may enhance velopharyngeal closure, potentially avoiding further corrective surgery.
Area of Science:
- Pediatric Otolaryngology
- Speech-Language Pathology
- Craniofacial Surgery
Background:
- Tonsillar hypertrophy can cause airway obstruction in children with repaired cleft palate and velopharyngeal insufficiency.
- The impact of tonsillectomy on velopharyngeal function in this specific patient group requires detailed assessment.
Purpose of the Study:
- To evaluate the effect of hypertrophied tonsils on velopharyngeal function in children with a history of cleft palate repair.
- To quantify the impact of tonsillectomy on velopharyngeal closure and speech resonance postoperatively.
Main Methods:
- A case series design was employed, involving twelve children with repaired cleft palate and tonsillar hypertrophy.
- Preoperative and postoperative assessments included auditory perceptual speech evaluation, nasalance scoring, and flexible nasopharyngoscopy to assess velopharyngeal closure.
Main Results:
- Significant improvements were observed in speech parameters, including reduced hypernasality and nasal air emission, along with better pressure consonant production.
- Postoperative nasalance scores showed significant improvement, and a reduction in the velopharyngeal gap was noted.
- While not statistically significant, three patients achieved complete velopharyngeal closure after tonsillectomy.
Conclusions:
- Hypertrophied tonsils can negatively affect velopharyngeal function in children with repaired cleft palates.
- Tonsillectomy offers significant benefits, improving speech resonance and velopharyngeal closure, potentially obviating the need for secondary corrective surgeries.
Related Concept Videos
Chronic Pharyngitis
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis II: Management
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Tonsillitis I: Introduction
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
Pharynx
The pharynx, a tubular structure framed by skeletal muscle and lined with mucous membrane, extends continuously from the nasal cavities. It is segmented into three major areas: the nasopharynx, oropharynx, and laryngopharynx.
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Anatomy of Respiratory System I: Upper Respiratory Tract
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.

