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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
DREAM--a novel approach for robust, ultrafast, multislice B₁ mapping
1Philips Research Laboratories, Hamburg, Germany. kay.nehrke@philips.com
Magnetic Resonance in Medicine
|January 19, 2012
Summary
A new B₁-mapping method, dual refocusing echo acquisition mode, achieves whole-volume coverage in one second. This fast MRI technique accurately measures flip angles and provides B₀ and transceive phase maps with low SAR.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Medical Physics
- Radiology
Background:
- Accurate B₁-field mapping is crucial for quantitative MRI.
- Existing methods are often slow, limiting their clinical applicability.
- Faster B₁-mapping can improve imaging efficiency and enable new applications.
Purpose of the Study:
- To introduce a novel, rapid multislice B₁-mapping technique.
- To evaluate the accuracy and performance of the proposed method.
- To demonstrate its utility in in vivo human imaging.
Main Methods:
- Development of the dual refocusing echo acquisition mode (DREAM) technique.
- Utilizing a Stimulated Echo Acquisition Mode (STEAM) preparation followed by a gradient echo sequence.
- Simultaneous measurement of STEAM and gradient echoes to determine flip angles.
Main Results:
- Achieved whole transmit coil volume coverage in one second, over ten times faster than conventional methods.
- Method is insensitive to susceptibility/chemical shift effects and provides B₀ and transceive phase maps.
- Demonstrated low T₁/T₂ dependence and low specific absorption rate (SAR).
- Validated accuracy through phantom experiments and in vivo imaging on abdomen, legs, and head.
Conclusions:
- The dual refocusing echo acquisition mode (DREAM) offers a significantly faster and accurate B₁-mapping solution.
- Its robustness and efficiency make it suitable for advanced MRI applications, including radiofrequency shimming.
- The method shows promise for routine clinical use, enhancing quantitative MRI capabilities.

