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Updated: May 25, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization

Mark E Fitzgerald1, Carol A Mulrooney, Jeremy R Duvall

  • 1Chemical Biology Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.

ACS Combinatorial Science
|January 19, 2012
PubMed

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