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Related Experiment Video

Updated: May 25, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

CODEX: exploration of semantic changes between ontology versions.

Michael Hartung¹, Anika Gross, Erhard Rahm

¹Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany. hartung@izbi.uni-leipzig.de

Bioinformatics (Oxford, England)

|January 19, 2012

Summary

This summary is machine-generated.

Life science ontologies evolve, necessitating tracking changes between versions. CODEX (Complex Ontology Diff Explorer) offers a tool to identify and analyze these semantic differences effectively.

Related Experiment Videos

Last Updated: May 25, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Area of Science:

Bioinformatics
Ontology Engineering
Life Sciences

Background:

Life science ontologies are dynamic and frequently updated to incorporate new knowledge and user needs.
Tracking modifications between ontology versions is crucial for maintaining data consistency and understanding scientific advancements.

Purpose of the Study:

To present CODEX (Complex Ontology Diff Explorer), a novel tool for identifying and analyzing semantic changes between two ontology versions.
To provide users with an interactive platform for understanding ontology evolution.

Main Methods:

Developing a computational approach to detect differences between successive ontology versions.
Implementing an interactive exploration interface for visualizing and analyzing identified semantic changes.

Main Results:

CODEX successfully determines semantic modifications between ontology versions.
The tool enables users to interactively explore these differences through multiple analytical views.

Conclusions:

CODEX facilitates a deeper understanding of ontology evolution in the life sciences.
The tool enhances the usability and interpretability of ontology version comparisons.