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Updated: May 25, 2026

Finite Element Modelling of a Cellular Electric Microenvironment
Published on: May 18, 2021
A data-driven modeling approach to stochastic computation for low-energy biomedical devices.
Kyong Ho Lee1, Kuk Jin Jang, Ali Shoeb
1Princeton University, Princeton, NJ 08540, USA. kyonglee@princeton.edu
Data-driven methods can model complex patient signals and overcome hardware errors in low-power devices. This approach maintains high performance in electroencephalogram (EEG) seizure detection and electrocardiogram (ECG) arrhythmia classification, even with significant fault rates.
Area of Science:
- Biomedical Engineering
- Signal Processing
- Hardware Reliability
Background:
- Low-power devices for physiological signal analysis enable closed-loop systems.
- Hardware errors in ultra-low-power platforms are a significant limitation.
Purpose of the Study:
- To demonstrate data-driven methods for modeling and overcoming hardware errors in physiological signal processing.
- To achieve robust performance in low-power biomedical devices despite hardware faults.
Main Methods:
- Data-driven modeling of physiological signals (EEG, ECG) and hardware error sources (SRAM bit-cell errors, logic-gate stuck-at faults).
- Synthesis of EEG-based seizure detection and ECG-based arrhythmia-beat classification to logic-gate implementation.
- Evaluation using patient data from CHB-MIT and MIT-BIH databases.
Main Results:
- Data-driven methods effectively model and mitigate prominent hardware error sources with minimal overhead.
- Achieved performance comparable to error-free hardware even at high fault rates (SRAM up to 0.5, logic up to 7x10^-2).
- Maintained high accuracy despite computational bit error rates reaching 50%.
Conclusions:
- Data-driven approaches offer a viable solution to hardware errors in ultra-low-power biomedical devices.
- This methodology enhances the reliability of real-time physiological monitoring and closed-loop therapeutic systems.
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