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Updated: May 25, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
A multiple-input multiple-output system for modeling the cardiac dynamics
Jorge E Monzon1, Carlos Alvarez Picaza, Maria I Pisarello
1Universidad Nacional del Nordeste, Corrientes, Argentina. jemonzon@unne.edu.ar
Abstract:
We describe the dynamics of the cardiovascular system by finding the input-output relationships in the state space of a functional cardiac model, based on state equations and observability criteria of control theory. The unit step response of the multiple-input multiple-output system model illustrates the damping effect of the arterial wall to the pulsatility of the heart. Our results show that hypertensive patients exhibit a lower inertia of the blood flow.
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