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Updated: May 25, 2026

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High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
Published on: December 23, 2013
Development of cost-effective biocompatible packaging for microelectronic devices.
Karen Qian1, Karl Malachowski, Paolo Fiorini
1IMEC, B-3001 Leuven, Belgium. Karen.Qian@imec.be
Summary
We developed a cost-effective, miniaturized packaging for implantable medical devices. Noble metal coatings like platinum prevent leaching, ensuring long-term biocompatibility and device safety.
Area of Science:
- Biocompatible Materials Science
- Medical Device Engineering
- Implantable Device Technology
Background:
- Developing safe and effective implantable medical devices requires robust packaging solutions.
- Current packaging methods face challenges with biocompatibility and long-term stability in physiological environments.
- Preventing metal ion leaching from device components is critical for patient safety.
Purpose of the Study:
- To propose a cost-effective, miniaturized, and biocompatible packaging method for implantable medical devices.
- To explore barrier materials and fabrication processes for individual die encapsulation.
- To ensure the long-term integrity and safety of implantable devices.
Main Methods:
- Investigated various common cleanroom materials for die encapsulation.
- Conducted accelerated aging tests using bio-fluid at elevated temperatures.
- Evaluated noble metals, specifically platinum (Pt), for electrode metallization.
- Performed calculations for cost-effectiveness of selective plating versus sputtering.
Main Results:
- Several common cleanroom materials demonstrated effectiveness in preventing metal leaching.
- Some conductive barrier materials degraded in bio-fluid under accelerated testing, indicating insufficient long-term resistance.
- Noble metals, particularly Pt, were identified as superior candidates for electrode covering.
- Selective plating of Pt was found to be more cost-effective than sputtering, with Pt recycling being crucial for sputter process cost reduction.
Conclusions:
- A novel, small, soft, and comfortable implantable package is achievable through explored methods.
- Noble metal coatings are essential for ensuring the long-term resistance of electrodes to body fluids.
- Optimized fabrication processes, including selective plating and material recycling, enhance cost-effectiveness for implantable device packaging.
