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Cantilever Bending of Murine Femoral Necks

Cantilever Bending of Murine Femoral Necks

Published on: January 5, 2022

Atypical fractures on long term bisphosphonates therapy.

W Hussein¹, C Cunningham, H Logan

¹Midland Regional Hospital, Mullingar, Co Westmeath. waelhussein@physicians.ie

Irish Medical Journal

|January 20, 2012

Summary

Bisphosphonates effectively reduce osteoporosis fracture risk. However, prolonged use may lead to atypical femoral fractures, a pattern requiring careful monitoring and characterization.

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Cantilever Bending of Murine Femoral Necks

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Published on: January 5, 2022

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

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Published on: December 9, 2022

Area of Science:

Orthopedics
Endocrinology
Pharmacology

Background:

Bisphosphonates are primary treatments for osteoporosis, effectively reducing fracture risk.
Prolonged bisphosphonate therapy is associated with an emerging pattern of specific fracture types.

Observation:

A case of atypical femoral fracture in a patient on long-term bisphosphonate therapy is presented.
The fracture was preceded by characteristic prodromal pain.

Findings:

Atypical femoral fractures exhibit distinct radiographic and clinical features.
These fractures are a potential complication of extended bisphosphonate use.

Implications:

Clinicians should be aware of atypical femoral fractures as a potential adverse effect of long-term bisphosphonate treatment.
Further research is needed to understand the pathogenesis and optimal management of these fractures.