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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Three cases of post-cataract surgery endophthalmitis due to Rhizobium (Agrobacterium) radiobacter
Viviane Moreau-Gaudry1, Christophe Chiquet, Sandrine Boisset
1Department of Ophthalmology, CHU Grenoble, Grenoble, France.
Abstract:
We present three unrelated post-cataract surgery endophthalmitis cases caused by Rhizobium radiobacter, hospitalized in three different hospitals. Early diagnosis was obtained in two cases by bacterial DNA detection in vitreous samples. All patients recovered from infection, but pars plana vitrectomy was needed in two patients due to rapid clinical deterioration.
Insights
Three patients developed endophthalmitis after cataract surgery due to Rhizobium radiobacter. Bacterial DNA detection aided early diagnosis, and all patients recovered, though two required vitrectomy.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Post-cataractic endophthalmitis is a severe intraocular infection.
- Rhizobium radiobacter is an uncommon cause of endophthalmitis.
Observation:
- Three distinct cases of endophthalmitis occurred in patients who had undergone cataract surgery.
- The causative agent identified in all three cases was Rhizobium radiobacter.
- These cases were unrelated and occurred in separate hospital settings.
Findings:
- Early diagnosis was achieved in two out of three patients through the detection of bacterial DNA in vitreous humor samples.
- All three patients successfully recovered from the infection.
- Two patients experienced rapid clinical deterioration necessitating pars plana vitrectomy.
Implications:
- Rhizobium radiobacter should be considered as a potential pathogen in post-cataract surgery endophthalmitis.
- Bacterial DNA detection in vitreous samples can facilitate prompt diagnosis and management.
- Aggressive management, including pars plana vitrectomy, may be required in severe cases.
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