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Updated: May 25, 2026

Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies
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Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies

Published on: January 22, 2015

Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3)

Rong Chen1, Anna Robinson, Dan Gordon

  • 1Research School of Biology, Australian National University, Canberra, Australia.

Biophysical Journal
|January 21, 2012
PubMed

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Voltage-gated Ion Channels

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Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
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Non-gated Ion Channels01:24

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