Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alcoholic liver disease.

J R Groover1

  • 1University of Florida Health Science Center, Jacksonville.

Emergency Medicine Clinics of North America
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

Alcoholic liver disease spans from fatty liver to severe failure. While abstinence and supportive care are primary, new treatments like prednisolone and colchicine show promise for fibrosis and overall outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Typhoid Fever.

Atlanta medical and surgical journal·2022
Same author

Indications for choledochoduodenostomy.

The American surgeon·1978
Same author

Cardiac arrhythmias during peritoneoscopy under local anesthesia.

The American journal of digestive diseases·1976
Same author

Immunologic tests for the detection of gastrointestinal cancers: status report on carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP).

Southern medical journal·1973
Same journal

Why Dispelling Myths and Misconceptions in Emergency Medicine Matters.

Emergency medicine clinics of North America·2026
Same journal

Myths and Misconceptions in Emergency Medicine.

Emergency medicine clinics of North America·2026
Same journal

Acute Otitis Media-Watch and Wait Is Not a Myth.

Emergency medicine clinics of North America·2026
Same journal

Hot or Not? Myths and Misconceptions About Antipyretics for Pediatric Fever.

Emergency medicine clinics of North America·2026
Same journal

Epinephrine Improves Outcomes in Out-Of-Hospital Cardiac Arrests.

Emergency medicine clinics of North America·2026
Same journal

Myth: Pretreatment Prevents Intravenous Contrast Reactions in the Emergency Department.

Emergency medicine clinics of North America·2026
See all related articles

Area of Science:

  • Hepatology
  • Gastroenterology
  • Internal Medicine

Background:

  • Alcoholic liver disease (ALD) encompasses a spectrum of liver damage, from fatty liver to end-stage cirrhosis.
  • The exact mechanisms of alcohol-induced hepatocyte injury are not fully understood but involve direct toxic and metabolic effects.
  • ALD complications include ascites, esophageal varices, and encephalopathy, significantly impacting patient prognosis.

Purpose of the Study:

  • To review the clinical manifestations, underlying mechanisms, and current therapeutic strategies for alcoholic liver disease.
  • To highlight emerging treatments and established management protocols for ALD complications.
  • To assess the long-term prognosis and survival rates associated with alcoholic liver disease.

Main Methods:

Related Experiment Videos

  • Literature review of alcoholic liver disease pathogenesis and clinical presentations.
  • Analysis of current and investigational therapeutic interventions for ALD.
  • Evaluation of management strategies for complications such as ascites and variceal hemorrhage.

    • Main Results:

    • ALD ranges from fatty liver to severe hepatitis and cirrhosis with life-threatening complications.
    • Abstinence and supportive care remain the cornerstone of ALD management.
    • Investigational therapies include prednisolone, anabolic steroids, and colchicine for fibrosis inhibition; large-volume paracentesis and sclerotherapy are effective for complications.

    Conclusions:

    • While new treatments offer potential, the prognosis for advanced alcoholic liver disease remains poor.
    • Effective management of ALD requires a multi-faceted approach addressing both the disease and its complications.
    • Further research is needed to improve long-term survival and outcomes for patients with alcoholic liver disease.