Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

H-Bonding Electron Donor-Acceptor (EDA) Complexes and Energy Transfer Synergy for Photocatalytic Synthesis of α-Substituted Vinyl Sulfones.

The Journal of organic chemistry·2026
Same author

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment.

Oncology reports·2025
Same author

Energy Transfer (EnT)-Mediated Stereoselective Aryl-Heterofunctionalization of Unactivated Alkynes via Radical Rearrangement.

The Journal of organic chemistry·2025
Same author

Using choroidal thickness to detect myopic macular degeneration.

International journal of ophthalmology·2024
Same author

Photocatalytic selective synthesis of (<i>E</i>)-β-aminovinyl sulfones and (<i>E</i>)-β-amidovinyl sulfones using Ru(bpy)<sub>3</sub>Cl<sub>2</sub> as the catalyst.

RSC advances·2024
Same author

Photocatalytic Radical Cascade Dehalogenation/Carbo-cyclization/Sulfonylation Leading to Indole- and Benzofuran-Based Benzylic Sulfones.

The Journal of organic chemistry·2023
Same journal

Crystal structure of 1-(piperidin-1-yl)butane-1,3-dione.

Acta crystallographica. Section E, Structure reports online·2015
Same journal

Crystal structure of methyl 1-methyl-3,5-diphenyl-7-tosyl-3,6,7,11b-tetra-hydro-pyrazolo-[4',3':5,6]pyrano[3,4-c]quinoline-5a(5H)-carboxyl-ate.

Acta crystallographica. Section E, Structure reports online·2015
Same journal

Crystal structure of 4-amino-1-(4-methyl-benz-yl)pyridinium bromide.

Acta crystallographica. Section E, Structure reports online·2015
Same journal

Crystal structure of (Z)-3-benz-yloxy-6-[(2-hy-droxy-anilino)methyl-idene]cyclo-hexa-2,4-dien-1-one.

Acta crystallographica. Section E, Structure reports online·2015
Same journal

Crystal structure of bis-(1-benzyl-1H-1,2,4-triazole) perchloric acid monosolvate.

Acta crystallographica. Section E, Structure reports online·2015
Same journal

Crystal structure of 2-(di-phenyl-phos-phanyl)phenyl 4-(hy-droxy-meth-yl)benzoate.

Acta crystallographica. Section E, Structure reports online·2015
See all related articles

Related Experiment Video

Updated: May 25, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

Published on: June 20, 2014

(4S,5S)-2-(2-Fluoro-phen-yl)-1,3-dioxolane-4,5-dicarboxamide.

Xin-Hua Li, De-Cai Wang, Bo-Nian Liu

    Acta Crystallographica. Section E, Structure Reports Online
    |January 21, 2012
    PubMed
    Summary
    This summary is machine-generated.

    The crystal structure of C(11)H(11)FN(2)O(4) reveals a five-membered ring with an envelope conformation. Intramolecular and intermolecular hydrogen bonds were observed, influencing molecular interactions.

    More Related Videos

    Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
    10:44

    Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

    Published on: May 15, 2019

    Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
    08:51

    Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core

    Published on: October 24, 2017

    Related Experiment Videos

    Last Updated: May 25, 2026

    Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
    06:34

    Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)

    Published on: June 20, 2014

    Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
    10:44

    Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

    Published on: May 15, 2019

    Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
    08:51

    Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core

    Published on: October 24, 2017

    Area of Science:

    • Crystallography
    • Molecular structure analysis
    • Organic chemistry

    Background:

    • Understanding molecular conformations is crucial in chemistry.
    • Hydrogen bonding plays a significant role in crystal packing and molecular interactions.

    Purpose of the Study:

    • To elucidate the molecular structure and conformation of the title compound, C(11)H(11)FN(2)O(4).
    • To investigate the presence and role of intramolecular and intermolecular hydrogen bonds in the crystal structure.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
    • Conformational analysis of the five-membered ring was performed.
    • Identification and analysis of hydrogen bonding networks (N-H⋯F and N-H⋯O).

    Main Results:

    • The five-membered ring in C(11)H(11)FN(2)O(4) adopts an envelope conformation.
    • An intramolecular hydrogen bond of the N-H⋯F type was identified.
    • Intermolecular N-H⋯O hydrogen bonds were observed, leading to the formation of a linked crystal structure.

    Conclusions:

    • The study provides detailed structural insights into C(11)H(11)FN(2)O(4).
    • The observed hydrogen bonding patterns are key features of the compound's crystal packing and molecular assembly.