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Updated: May 25, 2026

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization
Published on: September 15, 2018
MicroRNAs: Novel Regulators of the Heart
1Key Laboratory of Arrhythmias, Ministry of Education, China (Tongji University), Shanghai 200065, China.
Abstract:
MicroRNAs are approximately 22 nucleotides in length, and they play central roles in the regulation of gene expression. MicroRNAs participate in many essential biological processes, such as cell proliferation, differentiation, apoptosis and stress. Emerging evidence has indicated that microRNAs are novel regulators involved in cardiac physiology and pathophysiology, including the regulation of cardiac physiological function and participation in the genesis of cardiac diseases. Although several challenges remain, microRNAs might have a promising diagnostic and therapeutic potential in cardiac diseases.
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