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Published on: November 20, 2015
Epidemiology of late and moderate preterm birth
Carrie K Shapiro-Mendoza1, Eve M Lackritz
1Maternal and Infant Health Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Mailstop K-23, 4770 Buford Highway, NE, Atlanta, GA 30341-3717, USA. ayn9@cdc.gov
Insights
Preterm birth impacts 12.5% of US births, with Black infants facing higher risks. Recent increases are linked to late preterm births (34-36 weeks), highlighting associated infant morbidity and mortality risks.
Area of Science:
- Neonatal health
- Reproductive epidemiology
- Perinatal outcomes
Background:
- Preterm birth affects 12.5% of US births, disproportionately impacting Black mothers.
- The preterm birth rate has risen 33% in 25 years, primarily due to late preterm births (34-36 weeks' gestation).
- Subtle morbidity and mortality risks in moderate (32-33 weeks) and late preterm infants are gaining attention.
Purpose of the Study:
- To summarize the epidemiology of moderate and late preterm birth.
- To review recent trends and risk factors.
- To highlight emerging knowledge on associated morbidity and mortality.
Main Methods:
- Epidemiological data review.
- Analysis of recent trends in preterm birth.
- Synthesis of current research on preterm infant outcomes.
Main Results:
- Preterm birth rates have increased, driven by late preterm deliveries.
- Black infants experience significantly higher preterm birth and mortality risks.
- Moderate and late preterm births are associated with respiratory, infectious, and neurocognitive complications.
Conclusions:
- Understanding the epidemiology and risks of moderate and late preterm birth is crucial.
- Addressing disparities in preterm birth outcomes for Black mothers is a priority.
- Further research is needed to fully characterize and mitigate the risks of late preterm delivery.
Abstract:
Preterm birth affects 12.5% of all births in the USA. Infants of Black mothers are disproportionately affected, with 1.5 times the risk of preterm birth and 3.4 times the risk of preterm-related mortality. The preterm birth rate has increased by 33% in the last 25 years, almost entirely due to the rise in late preterm births (34-36 weeks' gestation). Recently attention has been given to uncovering the often subtle morbidity and mortality risks associated with moderate (32-33 weeks' gestation) and late preterm delivery, including respiratory, infectious, and neurocognitive complications and infant mortality. This section summarizes the epidemiology of moderate and late preterm birth, case definitions, risk factors, recent trends, and the emerging body of knowledge of morbidity and mortality associated with moderate and late preterm birth.
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