Related Experiment Video
Updated: May 25, 2026

Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
Published on: May 10, 2022
Mayer-Rokitansky-Küster-Hauser syndrome: a review of 245 consecutive cases managed by a multidisciplinary approach
D Keith Edmonds1, Gillian L Rose, Michelle G Lipton
1Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom. DouglasKeith.Edmonds@imperial.nhs.uk
Objective:
To understand the efficacy of vaginal dilators in the management of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.
Design:
Retrospective sequential study.
Setting:
Hospital.
Patient(S):
245 women.
Intervention(S):
Vaginal dilators.
Main Outcome Measure(S):
Functional vaginal length and sexual satisfaction.
Result(S):
Of the patients who completed the program, 232 (94.9%) achieved a successful vaginal length (defined as greater than 6 cm in length and maximum width throughout the vagina and especially at the apex) and sexual function. When the program was completed by all patients, 100% of patients were successful.
Conclusion(S):
Vaginal dilator therapy is the treatment of first choice for creation of the vagina in MRKH syndrome, and the success rates suggest that surgery is rarely, if ever, required.
Related Concept Videos
Urinary Tract Calculi VI: Surgical Management
Mitral Valve Prolapse II: Assessment and Management
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Urinary Tract Calculi III: Medical Management