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Updated: May 25, 2026

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression
Published on: April 18, 2025
Cystic fibrosis: an unusual neonatal presentation
Koravangattu Sankaran1, Mila Kalapurackal, Sheldon Wiebe
1Department of Paediatrics, College of Medicine, University of Saskatchewan, Saskatoon, Canada. k.sankaran@usask.ca
Abstract:
In mechanically ventilated neonates it is not uncommon to observe obstructive atelectasis from various causes. However it is extremely rare to see mucous plugging and massive pulmonary atelectasis in the absence of infection, aspiration, and respiratory distress syndrome in the first couple of days of life. In this report we describe a neonate born with cystic fibrosis (CF) who presented to us with hypoxic respiratory failure, pulmonary hypertension, and hypercarbia without lactic acedemia from sticky mucous plugging and massive lung collapse. Neonatal respiratory distress and wide spread pulmonary atelectasis has not been reported in infants born with CF.
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