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Effect of elective percutaneous coronary intervention on left ventricular function in patients with coronary artery

Younes Nozari1, Nader Jangi Oskouei, Zahra Khazaeipour

  • 1Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Iran.

Acta Medica Iranica
|January 24, 2012
PubMed

Insights

Percutaneous coronary intervention (PCI) improved left ventricular (LV) systolic and diastolic function in patients with coronary artery disease. Echocardiography showed enhanced ejection fraction and reduced diastolic dysfunction after PCI.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Coronary artery disease (CAD) is a leading global cause of death.
  • Treatment options include medication, coronary artery bypass graft (CABG), and percutaneous coronary intervention (PCI).

Purpose of the Study:

  • To evaluate the impact of PCI on left ventricular (LV) systolic and diastolic function using echocardiography.
  • To assess changes in LV function before and after PCI in CAD patients.

Main Methods:

  • 115 patients with CAD undergoing PCI were enrolled.
  • Echocardiography was performed pre-PCI, post-PCI (1 day), and 3-6 months later.
  • LV systolic (ejection fraction) and diastolic functions were measured and analyzed.

Main Results:

  • Mean ejection fraction (EF) increased from 40.52% pre-PCI to 44.0% at 3-6 months post-PCI.
  • Mild to moderate diastolic dysfunction improved significantly post-PCI, with 74% of patients showing improvement.
  • Diastolic function remained improved at the 3-6 month follow-up.

Conclusions:

  • PCI effectively improves LV systolic function, indicated by increased ejection fraction.
  • PCI leads to significant improvement in LV diastolic function in patients with coronary artery disease.
  • The positive effects of PCI on LV function are sustained for at least 3-6 months post-procedure.

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