Prospective randomised evaluation of a new cell saving device in elective aortic reconstruction

Area of Science:

• Cardiovascular Surgery
• Transfusion Medicine
• Medical Device Technology

Background:

• Homologous blood transfusions carry risks for patients and staff.
• Autotransfusion aims to mitigate these risks by using the patient's own blood.
• Elective aortic reconstructions often require significant blood transfusions.

Purpose of the Study:

• To evaluate the clinical and hematological effects of autotransfusion using the Haemolite device.
• To assess the safety and efficacy of cell salvage in elective aortic surgery.
• To determine the impact on homologous blood usage and patient outcomes.

Main Methods:

• A study of 67 patients undergoing aortic reconstructions.
• Comparison between a control group and patients undergoing autotransfusion with the Haemolite device.
• Analysis of blood transfusion volumes, wound drainage, and patient morbidity/mortality.

Main Results:

• Median bank blood transfused decreased from 4 units to 0 (P < 0.0001).
• Wound drainage showed a non-significant decrease (250 ml to 200 ml, P = 0.12).
• No bleeding diathesis, morbidity, or mortality related to autotransfusion was observed; hospital stay was reduced.

Conclusions:

• The Haemolite device is a safe and effective option for autotransfusion in elective aortic surgery.
• Autotransfusion significantly reduces the need for homologous blood, benefiting patients and staff.
• This technique offers a viable alternative to allogeneic blood transfusion in this surgical context.