Related Experiment Video
Updated: May 25, 2026

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
Published on: February 8, 2018
Post-stop-signal adjustments: inhibition improves subsequent inhibition
Patrick G Bissett1, Gordon D Logan
1Department of Psychology, Vanderbilt University, Nashville, TN 37240, USA. patrick.g.bissett@vanderbilt.edu
Abstract:
Performance in the stop-signal paradigm involves a balance between going and stopping, and one way that this balance is struck is through shifting priority away from the go task, slowing responses after a stop signal, and improving the probability of inhibition. In 6 experiments, the authors tested whether there is a corresponding shift in priority toward the stop task, speeding reaction time to the stop signal. Consistent with this hypothesis, stop-signal reaction time (SSRT) decreased on the trial immediately following a stop signal in each experiment. Experiments 2-4 used 2 very different stop signals within a modality, and stopping improved when the stop stimulus repeated and alternated. Experiments 5 and 6 presented stop signals in different modalities and showed that SSRT improved only when the stop stimulus repeated within a modality. These results demonstrate within-modality post-stop-signal speeding of response inhibition.
Related Concept Videos
Feedback Inhibition
Cell Signaling Feedback Loops
Negative feedback loops
Most signaling systems have negative feedback loops that can perform different functions such as output limiter, and adaptation.
Output limiter
Upon receiving an input signal, the cellular response rapidly increases until a threshold is reached. Beyond this threshold, a negative feedback loop...
Desensitization and Tachyphylaxis
Several...
Amplifying Signals via Enzymatic Cascade
Long-term Potentiation
Hebbian LTP
LTP can occur when presynaptic neurons...
Long-term Potentiation
