Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anatomy of the Eyeball

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...

Cranial Nerves: Types Part I

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Development of the human cerebellum from midgestation to the perinatal period: A morphological study.

Brain & development·2025

Same author

Successful pregnancy and delivery following microdissection testicular sperm extraction and intracytoplasmic sperm injection for non-obstructive azoospermia after microsurgical varicocelectomy: A case report and review of the literature.

The journal of obstetrics and gynaecology research·2024

Same author

Development of the human medullary arcuate nucleus from mid-gestation to the perinatal period: A morphometric study.

Neuroscience letters·2023

Same author

Concordance between HokUS-10 Scoring and Transjugular Liver Biopsy for the Diagnosis of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Allogeneic Stem Cell Transplantation.

Transplantation and cellular therapy·2023

Same author

FDG PET/CT in Primary Retroperitoneal Serous Carcinoma.

Clinical nuclear medicine·2023

Same author

Immunohistological analysis of pathogenic infiltrates in the epidermis and liver of a patient with toxic epidermal necrolysis accompanied by vanishing bile duct syndrome.

The Journal of dermatology·2022

Search research articles

Related Experiment Video

Updated: May 25, 2026

Assessment of Zebrafish Lens Nucleus Localization and Sutural Integrity

Assessment of Zebrafish Lens Nucleus Localization and Sutural Integrity

Published on: May 6, 2019

Development of the human abducens nucleus: a morphometric study.

Katsuyuki Yamaguchi¹, Koichi Honma

¹Department of Pathology, Dokkyo University School of Medicine, Tochigi, Japan. katsuyukiy@cc9.ne.jp

Brain & Development

|January 25, 2012

Summary

This summary is machine-generated.

The human abducens nucleus develops rapidly late in gestation, showing distinct neuron types. This study details its histology and morphometry in preterm infants, offering insights into early eye movement control development.

More Related Videos

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

Published on: May 26, 2021

Related Experiment Videos

Last Updated: May 25, 2026

Assessment of Zebrafish Lens Nucleus Localization and Sutural Integrity

Assessment of Zebrafish Lens Nucleus Localization and Sutural Integrity

Published on: May 6, 2019

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

Published on: May 26, 2021

Area of Science:

Neuroscience
Developmental Biology
Human Anatomy

Background:

The abducens nucleus controls horizontal eye movements by innervating the lateral rectus muscle.
Human fetal and neonatal abducens nucleus cytoarchitecture is understudied compared to other vertebrates.

Purpose of the Study:

To investigate the histology and morphometry of the human abducens nucleus in preterm infants.
To document the developmental changes in the abducens nucleus from 20 to 43 postmenstrual weeks.

Main Methods:

Examined 12 human brains from preterm infants (20-43 postmenstrual weeks).
Utilized celloidin-embedded serial sections stained with Klüver-Barrera and other conventional histological methods.

Main Results:

The abducens nucleus was identifiable by 20 weeks, with distinct neurons and glial cells.
Neuron morphology and Nissl body development (granular to tigroid) changed with gestational age.
Nuclear volume increased exponentially, neuronal profile areas showed a widening non-normal distribution, and average neuronal size increased linearly with age.

Conclusions:

The human abducens nucleus exhibits rapid growth towards the end of gestation.
The nucleus contains heterogeneous neuronal populations with age-dependent maturation.