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A concise total synthesis of (±)- and (-)-okilactomycin D
1Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Organic Letters
|January 26, 2012
Abstract:
The spirotetronate okilactomycin D (7) has been efficiently synthesized by a route featuring a substrate-controlled, diastereoselective (8:1) intramolecular Diels-Alder (IMDA) reaction of 11. The assigned absolute configuration of (-)-7 was confirmed.
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