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Valorization of the Red Seaweed Gracilaria gracilis Through a Biorefinery Approach
Published on: November 21, 2023
In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae
María Guinea1, Virginia Franco, Lidia Araujo-Bazán
1Department of Pharmacology, University of Alcalá, Alcalá de Henares, and Dermatology Service, Hospital Ramon y Cajal, Madrid, Spain. maria.guinea@uah.es
Abstract:
The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE.
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