Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy of allylestrenol combined with ritodrine in treating preterm labour with preeclampsia and associated risk factors for pregnancy outcomes.

American journal of translational research·2025
Same author

Predictive Value of Geriatric Nutritional Risk Index in Patients With Lower Extremity Peripheral Artery Disease: A Meta-Analysis.

Frontiers in nutrition·2022
Same author

Valorization of Polysaccharides From <i>Benincasa hispida</i>: Physicochemical, Moisturizing, and Antioxidant Skincare Properties.

Frontiers in pharmacology·2022
Same author

[Expression of a SARS-CoV-2 neutralizing nanobody in <i>Trichoderma reesei</i>].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2022
Same author

Detection of Stable Elite Haplotypes and Potential Candidate Genes of Boll Weight Across Multiple Environments via GWAS in Upland Cotton.

Frontiers in plant science·2022
Same author

Mechanism of Liver Regeneration During ALPPS.

Frontiers in cell and developmental biology·2022
Same journal

Denoising algorithm of Φ-OTDR systems based on adaptive fractional wavelet transform denoising.

Optics express·2026
Same journal

Millisecond photon-to-photon latency and high-speed volumetric projection system for optogenetics.

Optics express·2026
Same journal

Polarization-encoded coaxial structured light for high-precision 3D surface profilometry.

Optics express·2026
Same journal

Discrete freeform optical design based on collaborative optimization of point cloud and local normals.

Optics express·2026
Same journal

Ultrafast ghost imaging with 25 GHz speckle switching and wavelength-division multiplexing.

Optics express·2026
Same journal

Atomic vapor cells fabricated by femtosecond laser welding of standard-optical-quality glass.

Optics express·2026
See all related articles

Related Experiment Video

Updated: May 25, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

3D-visual laser-diode-based photoacoustic imaging.

Lvming Zeng1, Guodong Liu, Diwu Yang

  • 1Key Laboratory of Optic-Electronic and Communication, Jiangxi Sciences and Technology Normal College, Nanchang, China. zenglvming@163.com

Optics Express
|January 26, 2012
PubMed
Summary
This summary is machine-generated.

A new, inexpensive, and portable laser-diode photoacoustic imaging (LD-PAI) system offers 3D visualization of blood vessels. This compact system achieves high resolution, paving the way for more accessible medical imaging.

More Related Videos

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
05:32

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging

Published on: June 21, 2017

Pulsed Laser Diode-Based Desktop Photoacoustic Tomography for Monitoring Wash-In and Wash-Out of Dye in Rat Cortical Vasculature
06:46

Pulsed Laser Diode-Based Desktop Photoacoustic Tomography for Monitoring Wash-In and Wash-Out of Dye in Rat Cortical Vasculature

Published on: May 30, 2019

Related Experiment Videos

Last Updated: May 25, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
05:32

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging

Published on: June 21, 2017

Pulsed Laser Diode-Based Desktop Photoacoustic Tomography for Monitoring Wash-In and Wash-Out of Dye in Rat Cortical Vasculature
06:46

Pulsed Laser Diode-Based Desktop Photoacoustic Tomography for Monitoring Wash-In and Wash-Out of Dye in Rat Cortical Vasculature

Published on: May 30, 2019

Area of Science:

  • Biomedical Optics
  • Medical Imaging Technology
  • Photoacoustic Imaging

Background:

  • Photoacoustic imaging (PAI) offers non-ionizing deep tissue visualization.
  • Current PAI systems can be expensive and bulky, limiting widespread clinical adoption.
  • Advancements in laser technology are crucial for developing cost-effective and portable PAI solutions.

Purpose of the Study:

  • To develop and demonstrate a compact, cost-effective, 3D-visual laser-diode-based photoacoustic imaging (LD-PAI) system.
  • To evaluate the system's performance in visualizing biological structures like blood vessels.
  • To reduce the size and cost of deep 3D-visual PAI systems for improved producibility.

Main Methods:

  • Utilized a pulsed semiconductor laser source operating at 905 nm with a 0.8 KHz repetition rate.
  • Achieved an energy density of 2.35 mJ/cm² and a pulse energy of 5.6 μJ.
  • Employed raster-scanning to acquire 3D volumetric data and integrated the laser with optical components and a rotational stage for a compact source (10 × 3 × 3 cm³).

Main Results:

  • Successfully visualized preliminary 3D volumetric renderings of knotted and helical blood vessel phantoms.
  • Achieved an axial resolution of 1.1 mm and a lateral resolution of 0.5 mm.
  • Produced clear 2D photoacoustic image slices with varying thickness and orientation for detailed 3D analysis.

Conclusions:

  • The developed LD-PAI system is inexpensive, portable, and durable, demonstrating potential for deep 3D-visual PAI.
  • The system's compact design and high-resolution imaging capabilities support its future producibility.
  • This technology can significantly lower the cost and size barriers for advanced PAI applications.