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[A case of acute potassium bromate intoxication]
Fukuoka Igaku Zasshi = Hukuoka Acta Medica
|August 1, 1990
Summary
A man survived a potassium bromate ingestion suicide attempt, experiencing acute renal failure and auditory disturbance. While renal function recovered, anemia and severe hearing loss persisted, highlighting delayed complications of bromate poisoning.
Area of Science:
- Toxicology
- Nephrology
- Otolaryngology
Background:
- Potassium bromate (KBrO3) is a toxic chemical sometimes used in suicide attempts.
- Ingestion can lead to severe systemic toxicity, including acute kidney injury.
Observation:
- A 44-year-old male ingested KBrO3, presenting with gastrointestinal distress, anuric acute renal failure, and auditory disturbances.
- Treatment included direct hemoperfusion and hemodialysis.
- Clinical course revealed progressive anemia, pruritus, pain, headache, tinnitus, and dysgeusia.
Findings:
- Renal biopsy confirmed acute tubular necrosis in the regenerative phase.
- Acute renal failure was reversible following treatment.
- Persistent findings included mild anemia and severe, irreversible auditory impairment.
Implications:
- This case underscores the potential for severe, multi-systemic toxicity following potassium bromate ingestion.
- Delayed complications like anemia and sensorineural hearing loss can occur even after initial recovery from acute kidney injury.
- Highlights the importance of long-term monitoring for patients with significant bromate exposure.