Related Experiment Video
Updated: May 25, 2026
10:52
Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Primary extranodal marginal zone lymphoma - Epididymis
Shanmugasundaram Rajaian1, Marie Therese Manipadam, Sheila Nair
1Department of Urology, Christian Medical College Hospital, Ida Scudder Road, Vellore, Tamilnadu, India.
Summary
A rare case of epididymal lymphoma, specifically extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT), was diagnosed in an elderly male. This finding highlights lymphoma as a crucial differential diagnosis for unresponsive scrotal swelling.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Epididymal masses can present as scrotal swelling, often initially treated for inflammatory conditions like epididymoorchitis.
- Primary lymphomas of the epididymis are exceptionally rare, posing diagnostic challenges.
Observation:
- An elderly male presented with painful right scrotal swelling unresponsive to antibiotic treatment for presumed epididymoorchitis.
- Ultrasound revealed a hypoechoic vascular mass in the epididymal tail; fine needle aspirate cytology was inconclusive.
Findings:
- Excisional biopsy confirmed primary extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT) arising from the epididymis.
- This represents a highly unusual presentation of MALT lymphoma.
Implications:
- Lymphoma should be considered in the differential diagnosis of epididymal masses, particularly those unresponsive to standard conservative management.
- Early recognition and diagnosis of extranodal lymphomas are critical for appropriate patient management and treatment strategies.
Related Concept Videos
01:15Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:16Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
01:23Detailed Structure and Function of Lymph Nodes
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...