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Clinical trials in integrative therapies
Debra L Barton1, Deirdre R Pachman
1Mayo Clinic Cancer Center, Rochester, MN 55905, USA. barton.debra@mayo.edu
Seminars in Oncology Nursing
|January 28, 2012
Summary
Evidence for natural products and mind-body therapies in oncology symptom management is preliminary, primarily from Phase II trials. Further rigorous research is essential to define their role and integrate these therapies into patient care.
Area of Science:
- Integrative oncology
- Complementary and alternative medicine
Background:
- Natural products and mind-body therapies are increasingly explored for managing cancer symptoms.
- Existing evidence often stems from early-phase clinical trials.
Purpose of the Study:
- To review clinical trials on natural products and mind-body therapies for oncology symptom management.
- To discuss challenges in developing clinical trials for these interventions.
- To highlight innovative study designs in this field.
Main Methods:
- Systematic review of peer-reviewed literature.
- Analysis of clinical trial methodologies and findings.
Main Results:
- Most evidence for reviewed integrative therapies is preliminary, derived from Phase II trials.
- Innovative strategies and methodologies for studying these therapies have been demonstrated.
Conclusions:
- More research is needed to establish the role of integrative therapies in oncology symptom management.
- Critical evaluation of literature is necessary for patient education.
- Well-designed studies demonstrating clinical significance are crucial for advancing these therapies.
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