[Nosocomial outbreak due to Listeria monocytogenes in a neonatal unit]

Cecilia Tortajada1, Roser Porta, Mercedes Riba

  • 1Servicio de Epidemiología, Agencia de Salud Pública de Barcelona, CIBER de Epidemiologia y Salud Pública (CIBERESP), Barcelona, España. ctortaja@aspb.cat

Abstract

Insights

A Listeria monocytogenes outbreak occurred in a neonatal intensive care unit, affecting three infants. Strict hygiene adherence is crucial to prevent such nosocomial infections.

Area of Science:

  • Neonatal intensive care unit (NICU) epidemiology
  • Infectious disease outbreak investigation
  • Bacterial nosocomial infections

Background:

  • Description of a Listeria monocytogenes outbreak within a neonatal intensive care unit setting.
  • Highlights the vulnerability of neonates to healthcare-associated infections.

Observation:

  • Investigation involved questionnaires, environmental assessments, and molecular typing.
  • Molecular studies confirmed the outbreak was caused by Listeria monocytogenes.

Findings:

  • Three neonates were affected by the Listeria monocytogenes outbreak.
  • While the exact transmission route remained unclear, cross-infection was highly suspected.
  • Genetic analysis confirmed the nosocomial nature of the outbreak.

Implications:

  • Emphasizes the critical importance of stringent adherence to universal hygiene standards.
  • Underscores the need for robust infection control protocols in NICUs to prevent L. monocytogenes spread.
  • Highlights the potential for cross-infection in vulnerable neonatal populations.

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...