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Updated: May 25, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
[Nosocomial outbreak due to Listeria monocytogenes in a neonatal unit]
Cecilia Tortajada1, Roser Porta, Mercedes Riba
1Servicio de Epidemiología, Agencia de Salud Pública de Barcelona, CIBER de Epidemiologia y Salud Pública (CIBERESP), Barcelona, España. ctortaja@aspb.cat
Introduction:
Description of an outbreak of Listeria monocytogenes in a neonatal intensive care unit.
Methods:
A questionnaire, environmental investigation and molecular study were performed.
Results:
We identified a nosocomial outbreak of L. monocytogenes, confirmed by the genetic study, in a neonatal intensive care unit. Three infants were affected. Although the transmission mechanism could not be elucidated, cross-infection was strongly suggested.
Conclusion:
Adherence to universal hygiene standards is necessary to avoid nosocomial outbreaks.
Insights
A Listeria monocytogenes outbreak occurred in a neonatal intensive care unit, affecting three infants. Strict hygiene adherence is crucial to prevent such nosocomial infections.
Area of Science:
- Neonatal intensive care unit (NICU) epidemiology
- Infectious disease outbreak investigation
- Bacterial nosocomial infections
Background:
- Description of a Listeria monocytogenes outbreak within a neonatal intensive care unit setting.
- Highlights the vulnerability of neonates to healthcare-associated infections.
Observation:
- Investigation involved questionnaires, environmental assessments, and molecular typing.
- Molecular studies confirmed the outbreak was caused by Listeria monocytogenes.
Findings:
- Three neonates were affected by the Listeria monocytogenes outbreak.
- While the exact transmission route remained unclear, cross-infection was highly suspected.
- Genetic analysis confirmed the nosocomial nature of the outbreak.
Implications:
- Emphasizes the critical importance of stringent adherence to universal hygiene standards.
- Underscores the need for robust infection control protocols in NICUs to prevent L. monocytogenes spread.
- Highlights the potential for cross-infection in vulnerable neonatal populations.
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