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Updated: May 25, 2026

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
Published on: April 3, 2015
Vascular graft infections
Michael H Young1, Gilbert R Upchurch, Preeti N Malani
1Division of Infectious Diseases, University of Kentucky School of Medicine, University of Kentucky, 800 Rose Street, MN-672, Lexington, KY 40536, USA. myoun4@uky.edu
Abstract:
Prosthetic vascular grafting is a commonly performed procedure that is central to the management of arterial disease and renal failure. Though rare, vascular graft infections (VGI) are potentially devastating, and carry a high rate of mortality and amputation. Despite extensive research and clinical experience, VGI remain a daunting therapeutic challenge for surgeons and infectious disease specialists. This article reviews the pathogenesis of VGI, in particular the role of biofilms, as well as the current state of clinical management including diagnostic modalities, surgical options for treatment, antimicrobial therapy, and preventive measures.
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