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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Animal Model of Implant-Associated Infections in Mice
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Published on: June 27, 2025

Breast implant infections.

Laraine L Washer1, Karol Gutowski

  • 1Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, 3119 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5378, USA. laraine@med.umich.edu

Infectious Disease Clinics of North America
|January 31, 2012
PubMed
Summary
This summary is machine-generated.

Breast implant infections, often from skin bacteria, affect 1.1% to 2.5% of augmentation and up to 35% of reconstruction surgeries. Diagnosis involves clinical signs and fluid cultures, with removal being the common management.

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Area of Science:

  • Plastic Surgery
  • Infectious Diseases
  • Medical Device Infections

Background:

  • Breast implant surgery, for augmentation or reconstruction, carries a risk of infection.
  • Infections can manifest immediately post-surgery or years later.
  • Skin flora are the most common causative organisms.

Purpose of the Study:

  • To summarize the incidence, diagnosis, and management of breast implant infections.
  • To highlight key diagnostic criteria and treatment strategies.

Main Methods:

  • Review of clinical presentation, including pain, swelling, erythema, and drainage.
  • Utilizing ultrasound-guided cultures of periprosthetic fluid for diagnosis.
  • Analysis of common management approaches, including implant removal.

Main Results:

  • Infection rates range from 1.1% to 2.5% for augmentation and up to 35% for reconstruction.
  • Clinical signs and fluid cultures are crucial for diagnosis.
  • Implant removal is the standard treatment, with salvage considered in specific cases.

Conclusions:

  • Breast implant infections are a significant complication, particularly in reconstruction.
  • Prompt diagnosis via clinical assessment and fluid culture is essential.
  • Management typically requires implant explantation.