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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

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In vitro characteristics of cryopreserved platelet concentrates reconstituted by fresh frozen or lyophilized plasma.

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Related Experiment Video

Updated: May 25, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
09:49

Routine Screening Method for Microparticles in Platelet Transfusions

Published on: January 31, 2018

[Practice assessment in platelet transfusions].

C Martinaud1, N Chastagnet, A Sailliol

  • 1Fédération de biologie clinique, hôpital d'instruction des armées Percy, 101, avenue Henri-Barbusse, 92140 Clamart, France. christophe.martinaud@inserm.fr

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|January 31, 2012
PubMed
Summary
This summary is machine-generated.

Platelet transfusion guidelines are generally followed for thresholds, especially in oncology units. However, the delivered platelet dose is often lower than recommended, impacting transfusion efficacy.

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Last Updated: May 25, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
10:25

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

Published on: March 19, 2016

Area of Science:

  • Hematology
  • Transfusion Medicine

Context:

  • National guidelines for platelet transfusion (2003) dictate indications, thresholds, and dosage.
  • Platelet transfusion practices were evaluated in a medium-sized hospital focused on emergency and oncology care.

Purpose:

  • To assess adherence to national platelet transfusion guidelines in routine clinical practice.
  • To specifically evaluate the adherence to transfusion thresholds and the delivered platelet dose.

Summary:

  • A prospective study analyzed 235 platelet transfusions over 11 months.
  • Transfusion thresholds were followed in 71% of cases overall and 93% in oncology units.
  • Post-transfusion platelet increment above 20% was observed in 59% of cases, suggesting variable efficacy.

Impact:

  • Findings indicate good adherence to transfusion thresholds in high-usage units.
  • The study raises concerns about consistently under-dosing platelet transfusions compared to guidelines.
  • Results highlight potential areas for optimizing platelet transfusion strategies to improve efficacy.