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[Treatment of chronic kidney disease: therapeutic strategy]

Xavier Belenfant1, Wided Tabbi Anani, Mélanie Roland

  • 1Hôpital André-Grégoire, service de néphrologie dialyse, 93100 Montreuil-sous-Bois, France. xavier.belenfant@chi-andre-gregoire.fr

Presse Medicale (Paris, France : 1983)
|January 31, 2012
PubMed

Insights

Slowing chronic kidney disease (CKD) progression involves managing cardiovascular risk factors and complications. Key targets include blood pressure and proteinuria, with ACE inhibitors as a primary treatment, alongside lifestyle changes.

Area of Science:

  • Nephrology
  • Cardiology

Context:

  • Chronic kidney disease (CKD) is a progressive condition with significant cardiovascular risks.
  • Effective management aims to slow disease progression and mitigate complications.

Purpose:

  • To outline objectives for managing CKD, including slowing progression, addressing cardiovascular risk factors, treating complications, and preparing for renal replacement therapy.
  • To define principal treatment targets for blood pressure and proteinuria.

Summary:

  • The primary treatment strategy involves angiotensin-converting enzyme (ACE) inhibitors, lifestyle modifications, and dietary changes to achieve blood pressure <130/80 mmHg and proteinuria <0.5 g/day.
  • Clinical and laboratory assessments are tailored to CKD stage and progression rate.
  • Comprehensive, multidisciplinary management is crucial for patient outcomes.

Impact:

  • Comprehensive management can halt or slow CKD progression.
  • Reduces cardiovascular complications, the leading cause of mortality in CKD patients.
  • Improves long-term patient prognosis and quality of life.

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