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Updated: May 25, 2026

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Published on: September 28, 2016
Modifications in the nitric acid oxidation of D-glucose
Tyler N Smith1, Kirk Hash, Cara-Lee Davey
1Shafizadeh Rocky Mountain Center for Wood and Carbohydrate Chemistry, The University of Montana, Missoula, MT 59812, USA.
Abstract:
The nitric acid oxidation of D-glucose was reinvestigated in an effort to better understand and improve the oxidation and subsequent work up steps. The oxidation was carried out using a computer controlled reactor employing a closed reaction flask under an atmosphere of oxygen which allowed for a catalytic oxidation process with oxygen as the terminal oxidant. Removal of nitric acid from product included the use of both diffusion dialysis and nanofiltration methodologies. Product analysis protocols were developed using ion chromatography.
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