Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Absorption Spectroscopy: Atomization Methods

Atomic Absorption Spectroscopy: Atomization Methods

Atomic Absorption Spectroscopy (AAS) atomizes samples through flame atomization or electrothermal atomization. Flame atomization typically involves a nebulizer and spray chamber assembly to combine the sample with a fuel–oxidant mixture, creating a fine aerosol mist that enters a burner. Typically, the fuel and oxidant are combined in an approximately stoichiometric ratio. However, for atoms that are easily oxidized, a fuel-rich mixture may be more advantageous. Only about 5% of the aerosol...

Factors Affecting Dissolution: Particle Size and Effective Surface Area

Factors Affecting Dissolution: Particle Size and Effective Surface Area

Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are employed to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fabrication and Characterization of Nerolidol-Based Invasomes: Loading, Stability and Antimicrobial Applications.

Pharmaceutics·2026

Same author

Coaxial Jet Mixing for Pharmaceutical Nanocarrier Production: Experimental Analysis and Mechanistic Modeling.

Pharmaceutics·2026

Same author

Process-guided design of nanoliposomal vitamin D3: formulation, stability and quality by design mapping.

International journal of pharmaceutics·2026

Same author

Improving the Microbiological Safety of Raw Meat Through Visible Blue-Violet Light Irradiation.

Foods (Basel, Switzerland)·2026

Same author

Design of pH‑sensitive alginate-carbopol hydrogel patches for wound healing applications.

International journal of pharmaceutics·2025

Same author

Evaluation of the antimicrobial and cytotoxic activity of nerolidol encapsulated in a nanoliposome system.

Frontiers in veterinary science·2025

Search research articles

Related Experiment Video

Updated: May 25, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

Intensifying the microencapsulation process: ultrasonic atomization as an innovative approach.

Annalisa Dalmoro¹, Anna Angela Barba, Gaetano Lamberti

¹Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Fisciano, Italy.

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V

|January 31, 2012

Summary

This review explores ultrasonic atomization, a novel microencapsulation technique for pharmaceutical manufacturing. It offers intensified processes and reduced energy consumption compared to traditional methods.

More Related Videos

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

Published on: July 16, 2021

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Published on: September 13, 2012

Related Experiment Videos

Last Updated: May 25, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets

Published on: July 16, 2021

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Synthesis of Phase-shift Nanoemulsions with Narrow Size Distributions for Acoustic Droplet Vaporization and Bubble-enhanced Ultrasound-mediated Ablation

Published on: September 13, 2012

Area of Science:

Pharmaceutical Manufacturing
Chemical Engineering
Materials Science

Background:

Microencapsulation is a key process in pharmaceutical manufacturing.
Traditional methods face challenges in efficiency and energy consumption.

Purpose of the Study:

To review new microencapsulation approaches.
To focus on the emerging ultrasonic atomization technique.
To highlight the advantages of ultrasonic atomization.

Main Methods:

Review of scientific literature on microencapsulation.
Analysis of ultrasonic atomization fundamentals and novel aspects.

Main Results:

Ultrasonic atomization presents a promising alternative for microencapsulation.
The technique offers process intensification.
Low energy requirements are a significant advantage.

Conclusions:

Ultrasonic atomization is an emerging technique with significant potential in pharmaceutical manufacturing.
Its efficiency and low energy demand make it attractive for industrial applications.