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Updated: May 25, 2026
09:01
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
[Intracranial hypertension - Therapeutic options]
Christoph Rosenthal1, Stefan Wolf, Steffen Weber-Carstens
1Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin (Interdisziplinäre Neurointensivstation), Charite-Universitätsmedizin Berlin. christoph.rosenthal@charite.de
Summary
High intracranial pressure (ICP) can harm the brain, especially after traumatic brain injury. Current treatments for intracranial hypertension lack strong evidence despite their importance.
Area of Science:
- Neurology
- Neurosurgery
Context:
- Intracranial pressure (ICP) elevation is a critical concern in various neurological conditions.
- Sustained ICP above 20-25 mmHg can lead to secondary brain injury via compromised cerebral perfusion or direct neuronal damage.
- Traumatic brain injury (TBI) is a primary cause of critically increased ICP, with many treatment strategies originating from TBI research.
Purpose:
- To review the current treatment strategies for intracranial hypertension.
- To highlight the weak evidence base for many established treatments, despite their inclusion in clinical guidelines.
Summary:
- ICP management is crucial to prevent secondary brain injury and neurological deterioration.
- Treatments range from general measures to escalated medical and surgical interventions.
- Evidence supporting the efficacy of most ICP-lowering strategies remains limited.
Impact:
- This review underscores the need for more robust research into effective treatments for intracranial hypertension.
- Improved evidence-based strategies are essential for better patient outcomes and reduced socio-economic burden.
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