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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Community-acquired methicillin-resistant Staphylococcus aureus in nasal vestibular abscess
Marisa A Earley1, Mark E Friedel, Satish Govindaraj
1Department of Otolaryngology-Head and Neck Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA.
International Forum of Allergy & Rhinology
|January 31, 2012
Summary
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) frequently causes skin infections. This study found MRSA is the predominant pathogen in nasal vestibular abscesses, necessitating targeted antibiotic therapy.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Microbiology
Background:
- Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of skin and soft tissue infections.
- MRSA is not typically identified as the primary pathogen in nasal vestibular abscesses.
Purpose of the Study:
- To investigate the prevalence and antibiotic susceptibility of pathogens, particularly MRSA, in nasal vestibular abscesses.
- To inform clinical practice regarding the management of nasal vestibular abscesses.
Main Methods:
- A retrospective case series of 13 patients with nasal vestibular abscesses treated at a tertiary care center over 2.5 years.
- Cultures were obtained from all abscesses for bacterial identification and antibiotic susceptibility testing.
Main Results:
- Staphylococcus aureus was isolated in 100% of cases (13/13).
- Methicillin-resistant Staphylococcus aureus (MRSA) accounted for 92% (12/13) of the S. aureus isolates.
- MRSA isolates demonstrated high susceptibility to rifampin, trimethoprim-sulfamethoxazole, and tetracycline, but lower susceptibility to clindamycin, fluoroquinolones, and erythromycin.
Conclusions:
- MRSA is a predominant pathogen in nasal vestibular abscesses, contrary to previous assumptions.
- Clinicians should consider MRSA in the empiric treatment of nasal vestibular abscesses.
- Cultures and targeted antibiotic therapy, including MRSA coverage, are crucial for effective management.
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