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Updated: May 25, 2026

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
Published on: June 14, 2020
[Immunomorphological investigation of hypertrophied tonsils in children]
Abstract:
The immunohistochemical investigation of hypertrophied tonsils in children of different ages (group 1--up to 7 years old, group 2--7-11 years old, group 3--12 years and older) are presented. The expression and localization of viral antigen, sIgA and IgE, CD3+ and CD20+ cells in the tonsils tissue has studied. We've founded out a decreasing of viral antigens expression in the older age groups. The highest intensity of sIgA expression has been determined in the second group. The count of CD3+ cells in the germinal centers of follicles has increased in 2 and 3 groups.
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