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Updated: May 25, 2026

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
Published on: May 4, 2017
Rituximab in severe skin diseases: target, disease, and dose
Daniel D Bennett1, Maro Ohanian, Christian T Cable
1Department of Dermatology, Division of Hematology and Oncology, Scott and White Healthcare, Texas A&M Health Science Center College of Medicine. Temple, TX, USA.
Abstract:
New clinical indications for rituximab seem to appear every day. This review will trace the use of this monoclonal antibody from lymphoid malignancy, to classic autoimmune disease, and specifically severe autoimmune skin diseases. The history leading to different dosing schema with associated pharmacokinetic data will be discussed. A case of livedoid vasculopathy (atrophie blanche) responding to rituximab will illustrate how the response to therapy can help to elucidate previously obscure pathophysiology.
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