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Updated: May 25, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Primary central nervous system B cell lymphoma with features intermediate between diffuse large B cell lymphoma and
Liuyan Jiang1, Zhimin Li, Laura E Finn
1Department of Pathology, Mayo Clinic, Jacksonville, Florida 32224, USA.
Abstract:
B cell lymphoma with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma (DLBCL/BL) is a new lymphoma entity which is recognized in the current World Health Organization (WHO) classification (2008). We report a case of a primary central nervous system lymphoma (PCNSL) with findings consistent with DLBCL/BL. It is characterized by a very aggressive clinical course, and a widespread multifocal involvement of the CNS. Our case shows that a DLBCL/BL can manifest in the CNS alone without any systemic involvement.
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