Related Experiment Video
Updated: May 25, 2026

Behavioral Characterization of an Angelman Syndrome Mouse Model
Published on: October 20, 2023
Sibling relationships in individuals with Angelman syndrome: a comparative study
Victoria Love1, Lotte Richters, Robert Didden
1Ossining High School, New York, USA.
Objective:
Investigating the impact of Angelman syndrome on the sibling relationship.
Methods:
This study explored differences in sibling relationships between children with a typically-developing sibling (n = 55) and children with a sibling with Angelman syndrome (n = 44). Sibling relationships were compared on four factors and 16 sub-scales of the Sibling Relationship Questionnaire-Revised.
Results:
Results showed significant differences in mean scores on each of the four factors (i.e. Warmth/Closeness, Conflict, Rivalry and Dominance/Nurturance) and most of the sub-scales. ANCOVAs showed that demographic variables (number of siblings, living in a two-parent vs single parent household, gender, participant's age, place of residence) did not influence significant differences in sibling relationships between the two groups.
Conclusion:
Having a brother or sister with Angelman syndrome may influence the way in which the sibling perceives the sibling relationship. This may have important implications for family-centred intervention for this population.
Related Concept Videos
Relationship with Other Adult Family Members and Siblings
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Adler's Individual Psychology
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Relationship Formation
Multiple Allele Traits

