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New 10F soft and pliable polyurethane stents decrease the migration rate compared with conventional 10F polyethylene
Young Koog Cheon1, Hyoung-Chul Oh, Young Deok Cho
1Digestive Disease Center, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. yksky001@hanmail.net
Gastrointestinal Endoscopy
|February 4, 2012
Summary
A new polyurethane (PU) biliary stent significantly reduced migration compared to traditional polyethylene (PE) stents. While patency rates were similar, the PU stent
Area of Science:
- Gastroenterology
- Medical Devices
- Interventional Radiology
Background:
- Biliary stent migration is a frequent complication.
- Polyurethane (PU) stents, designed for softness, may reduce migration.
- Conventional polyethylene (PE) stents are prone to migration.
Purpose of the Study:
- To compare the migration rates of PU stents versus PE stents.
- To evaluate the efficacy of a novel PU stent in preventing biliary stent migration.
Main Methods:
- Prospective, comparative, randomized trial.
- Fifty patients with hilar stricture were randomized to receive either a PU or PE stent.
- Early proximal or distal migration was the primary outcome measured.
Main Results:
- The PU stent group showed significantly lower overall and distal migration rates (4.5% vs. 29% and 4.5% vs. 26.1%, respectively).
- No significant difference in migration was observed between benign and malignant strictures.
- Stent patency was similar between the PU and PE groups (median 148 days vs. 151 days).
Conclusions:
- The novel PU stent effectively decreased distal migration in patients with hilar stricture.
- While patency rates appear similar, the study lacked power to demonstrate equivalency.
- Further research with larger sample sizes is warranted to confirm patency equivalency.
