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Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
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Self-assembled Nano-layering at the Adhesive interface.

Y Yoshida1, K Yoshihara, N Nagaoka

  • 1Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8525, Japan. yasuhiro@md.okayama-u.ac.jp

Journal of Dental Research
|February 4, 2012
PubMed
Summary
This summary is machine-generated.

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Dental adhesives containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) form self-assembled nano-layers on tooth tissue. This nano-layering enhances bond durability and may explain the long-term clinical success of MDP-based dental adhesives.

Area of Science:

  • Biomaterials Science
  • Dental Materials Science
  • Nanotechnology in Dentistry

Background:

  • The Adhesion-Decalcification concept posits ionic interactions between functional monomers in dental adhesives and hydroxyapatite (HAp).
  • 10-methacryloyloxydecyl dihydrogen phosphate (MDP) is known to form self-assembled nano-layers via ionic bonding with HAp.
  • The occurrence of MDP-induced nano-layering on actual tooth tissue using commercial adhesives under clinical conditions requires investigation.

Purpose of the Study:

  • To investigate whether nano-layering occurs at the adhesive-dentin interface when using commercial MDP-containing dental adhesives (Clearfil SE Bond, Kuraray; Scotchbond Universal, 3M ESPE) following standard clinical protocols.
  • To characterize the chemical and ultrastructural properties of the adhesive-dentin interface formed by these adhesives.

Main Methods:

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  • Chemical characterization using X-ray Diffraction (XRD) and Energy-Dispersive X-ray Spectroscopy (EDS).
  • Ultrastructural analysis using (Scanning) Transmission Electron Microscopy (TEM/STEM).
  • Application of commercial MDP-containing adhesives (Clearfil SE Bond, Kuraray; Scotchbond Universal, 3M ESPE) following common clinical protocols.

Main Results:

  • Both Clearfil SE Bond and Scotchbond Universal exhibited nano-layering at the adhesive interface.
  • Nano-layering was observed within the hybrid layer and, notably for Clearfil SE Bond, extended into the adhesive layer itself.
  • The formation of self-assembled nano-layers, involving MDP-Ca salt formation, was confirmed.

Conclusions:

  • Commercial MDP-containing dental adhesives form self-assembled nano-layers on tooth dentin under clinically relevant conditions.
  • This nano-layering phenomenon, particularly evident with Clearfil SE Bond, contributes to a more biodegradation-resistant adhesive interface.
  • The observed nano-layering provides a potential explanation for the documented favorable clinical longevity of MDP-based dental adhesives.