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Related Concept Videos

ABC Transporters: Exporter01:31

ABC Transporters: Exporter

ATP-binding cassette or ABC transporter is the largest superfamily of integral membrane proteins. The transporters have transmembrane-binding domains (TMDs) and nucleotide-binding domains (NBDs). The TMDs are specific to their substrates, whereas the NBDs are similar to engines that complete ATP hydrolysis to complete the substrate transport. They can be full transporters consisting of two TMDs and NBDs, half transporters with one TMD and NBD, while some encoded with a single TMD or NBD are...
ABC Transporters: Importer01:27

ABC Transporters: Importer

ATP-binding cassette or ABC transporters are a class of ATP-driven pumps that hydrolyze ATP to move solutes across the membrane. They can be grouped into importers and exporters. While exporters are present in all domains of life, importers exist only in bacteria and some plants.
In bacteria, based on the number of transmembrane helices and the chemical nature of their substrates, the ABC importers can be divided into three types:
Active Transport01:14

Active Transport

Active transport is a critical biological process that allows cells to move solutes against an electrochemical gradient. This process requires direct energy input and is characterized by its selectivity, saturability, and susceptibility to competitive inhibition.
Primary active transporters, like Na+, K+ and -ATPase, directly utilize ATP to move ions across the membrane. These transporters play significant roles in various physiological processes. For instance, Na+, K+ and -ATPase maintain...
Carrier-Mediated Transport01:06

Carrier-Mediated Transport

Carrier-mediated transport is a pivotal process in drug absorption, particularly for lipid-insoluble drugs, and encompasses facilitated diffusion and active transport. Facilitated diffusion allows drugs to move along their concentration gradient without energy expenditure, while active transport utilizes ATP to drive drug movement against this gradient.
Active transport involves two types of membrane-spanning transporters: uptake and efflux. Uptake transporters are expressed in the small...
ATP Driven Pumps I: An Overview01:27

ATP Driven Pumps I: An Overview

ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and are...
Membrane Transporters01:31

Membrane Transporters

Transporters are essential membrane transport proteins with functions related to cell nutrition, homeostasis, communication, etc. Approximately 7% of all genes in the human genome code for transporters or transporter-related proteins.
Transporters are mainly composed of alpha-helices, built from bundles of ten or more helices traversing the plasma membrane. The solute-binding sites are located midway, where some of the helices are broken or distorted, making space for the binding site through...

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Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles
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Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles

Published on: December 31, 2019

Plant ABC Transporters.

Joohyun Kang, Jiyoung Park, Hyunju Choi

    The Arabidopsis Book
    |February 4, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Plant ATP-binding cassette (ABC) transporters are crucial for survival, involved in diverse functions from growth to stress response. This review highlights their importance in plant development and survival.

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    Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)
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    A Step-by-step Method for the Reconstitution of an ABC Transporter into Nanodisc Lipid Particles

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    Last Updated: May 25, 2026

    Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles
    13:16

    Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles

    Published on: December 31, 2019

    Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)
    09:35

    Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)

    Published on: November 29, 2014

    A Step-by-step Method for the Reconstitution of an ABC Transporter into Nanodisc Lipid Particles
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    A Step-by-step Method for the Reconstitution of an ABC Transporter into Nanodisc Lipid Particles

    Published on: August 31, 2012

    Area of Science:

    • Plant Biology
    • Molecular Biology
    • Biochemistry

    Background:

    • ATP-binding cassette (ABC) transporters are a large protein family in all organisms.
    • Plant genomes encode over 100 ABC transporters, with many functions yet to be analyzed.
    • These transporters are located in various plant cell membranes, performing diverse roles.

    Purpose of the Study:

    • To provide an overview of plant ABC transporter functions.
    • To emphasize the significance of ABC transporters in plant development and survival.

    Main Methods:

    • Literature review of existing research on plant ABC transporters.
    • Analysis of functional roles and substrate specificities.

    Main Results:

    • Plant ABC transporters are involved in detoxification, organ growth, nutrient uptake, and stress responses.
    • They transport various substrates, including lipids, phytate, and phytohormones like auxin and abscisic acid.
    • Over 100 ABC transporters are encoded in plant genomes, exceeding other organisms.

    Conclusions:

    • Plant ABC transporters are essential for multiple physiological processes.
    • Understanding their diverse functions is key to comprehending plant development and survival strategies.