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Updated: May 25, 2026
10:58
Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry
Published on: September 27, 2020
[Neurology]
J N Chabwine1, A R Rossetti, L Hirt
1Service de neurologie, Département de neurosciences cliniques, CHUV, Lausanne. jo.nsimy@gmail.com
Revue Medicale Suisse
|February 7, 2012
Summary
In 2011, advancements included new oral anticoagulants for atrial fibrillation, updated stroke risk scores, and faster multiple sclerosis diagnosis with new oral treatments. Novel epilepsy drugs and evolving Parkinson
Area of Science:
- Neurology
- Pharmacology
- Genetics
Context:
- 2011 saw significant advancements in managing neurological conditions.
- New diagnostic criteria and treatments emerged for atrial fibrillation, multiple sclerosis, epilepsy, and Parkinson disease.
- Research progressed in treating chronic dysimmune polyneuropathies and genetic myopathies.
Purpose:
- To review key 2011 developments in neurological treatments and diagnostics.
- To highlight new therapeutic options and updated risk prediction tools.
- To summarize progress in gene therapy for genetic myopathies.
Summary:
- New oral anticoagulants for atrial fibrillation and updated ABCD3-I score for TIA stroke risk.
- New McDonald criteria for faster multiple sclerosis diagnosis and fingolimod as the first oral treatment.
- New anti-epileptic drug retigabine; long-term neurological risks of sodium valproate in utero exposure.
- Deep brain stimulation expansion and extended-release dopamine agonists for Parkinson disease.
- Monoclonal antibodies and immunosuppressants for chronic dysimmune polyneuropathies.
- Progress in gene therapy for genetic myopathies.
Impact:
- Improved stroke risk prediction and management in atrial fibrillation.
- Faster multiple sclerosis diagnosis and new oral treatment options.
- Enhanced epilepsy treatment landscape and awareness of in utero drug exposure risks.
- Expanded therapeutic strategies for Parkinson disease.
- Alternative treatments for chronic dysimmune polyneuropathies.
- Promising future directions for genetic myopathy treatment through gene therapy.
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