Related Experiment Video
Updated: May 25, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Coronary artery calcium testing: dos and don'ts
Tamar S Polonsky1, Donald M Lloyd-Jones
1Section of Cardiology, Department of Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 6080, Chicago, IL 60637, USA. tpolonsky@medicine.bsd.uchicago.edu
Insights
Coronary heart disease (CHD) risk assessment often misses individuals. Coronary artery calcium (CAC) scoring enhances risk prediction beyond traditional factors, with guidelines to optimize its use.
Area of Science:
- Cardiology
- Preventive Medicine
- Medical Imaging
Background:
- Traditional risk factors are the cornerstone of coronary heart disease (CHD) screening.
- A significant number of adults experiencing CHD events are not identified as high-risk by conventional metrics.
- Observational studies suggest coronary artery calcium (CAC) scoring offers improved risk prediction.
Purpose of the Study:
- To evaluate the added value of coronary artery calcium (CAC) scoring in refining coronary heart disease (CHD) risk prediction.
- To provide practical guidance on the optimal application of CAC testing.
- To minimize potential harms associated with CAC testing.
Main Methods:
- Analysis of observational data on the predictive performance of CAC scores.
- Review of existing clinical practice guidelines for CHD risk assessment.
- Development of a list of best practices ('dos and don'ts') for CAC testing.
Main Results:
- Coronary artery calcium (CAC) scoring demonstrates improved risk prediction for coronary heart disease (CHD), independent of traditional risk factors.
- The study identifies key principles to enhance the utility of CAC testing.
- Recommendations are provided to ensure safe and effective implementation of CAC screening.
Conclusions:
- Coronary artery calcium (CAC) scoring is a valuable tool for enhancing coronary heart disease (CHD) risk stratification.
- Adherence to established principles can maximize the benefits of CAC testing.
- Optimized CAC testing can improve patient outcomes by identifying at-risk individuals missed by traditional methods.
Abstract:
Measurement of traditional risk factors remains the foundation of current clinical practice guidelines when screening for coronary heart disease (CHD) risk. However, many adults who experience CHD events are not identified as higher risk based on their traditional risk factors. Observational data show that the coronary artery calcium (CAC) score improves risk prediction, even after taking into account traditional risk factors. The authors have outlined several principles of CAC testing into a list of dos and don'ts to help maximize its potential benefit while minimizing potential harm.
More Related Videos
06:57Semi-Automatic Graphical Tool for Measuring Coronary Artery Spatially Weighted Calcium Score from Gated Cardiac Computed Tomography Images
Published on: September 22, 2023
10:28Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Coronary Artery Disease IV: Preventive Measures
Imaging Studies for Cardiovascular System V: CT
Coronary Artery Disease V: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview
Coronary Artery Disease I: Introduction