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Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...

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Related Experiment Video

Updated: May 25, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Obsessive compulsive disorder.

G Mustafa Soomro1

  • 1St. James Hospital, Portsmouth, UK.

BMJ Clinical Evidence
|February 7, 2012
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for obsessive compulsive disorder (OCD). It found various interventions, including behavioral therapy and serotonin reuptake inhibitors, effective for adults and children with OCD.

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Area of Science:

  • Psychiatry and Behavioral Sciences
  • Clinical Psychology
  • Pharmacology

Background:

  • Obsessive compulsive disorder (OCD) affects 1-1.5% of adults and 2.7% of children/adolescents.
  • OCD can have an episodic or continuous course, persisting in 40% of youth.
  • The disorder causes significant personal distress and social dysfunction.

Purpose of the Study:

  • To systematically review the effects of initial and maintenance treatments for OCD in adults.
  • To assess treatments for children and adolescents with OCD.
  • To evaluate interventions for adults with SRI-resistant OCD.

Main Methods:

  • Systematic review of 43 studies including systematic reviews, RCTs, and observational studies.
  • Searched major databases (Medline, Embase, Cochrane Library) up to April 2011.
  • Included harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • Evaluated the effectiveness and safety of numerous interventions for OCD.
  • Included treatments such as antipsychotics, behavioral therapy, CBT, ECT, psychosurgery, SRIs, and TMS.
  • Utilized GRADE evaluation for evidence quality.

Conclusions:

  • Information on the effectiveness and safety of various OCD interventions is presented.
  • The review covers treatments for different patient groups and treatment stages.
  • Evidence supports a range of therapeutic options for managing OCD.