Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic evaluation and clinical utility of C-MoKa for prenatal genetic testing.

Journal of translational medicine·2026
Same author

[Clinical and genetic analysis of a child with Relapsing encephalopathy with cerebellar ataxia due to variant of ATP1A3 gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2026
Same author

[Analysis of gene variant spectrum associated with Familial hypercholesterolemia in a regional population: A retrospective study based on exome sequencing of 15 841 cases].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2026
Same author

[Prenatal diagnosis and genetics analysis of a fetus with type 27 intellectual disability syndrome due to variant of SRRM2 gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2026
Same author

Ultra-broadband and compact TM-pass polarizer based on silicon nitride-assisted lithium niobate on insulator platform.

Optics express·2026
Same author

[Clinical characteristics and genetic analysis of three fetuses with Baraitser-Winter cerebrofrontofacial syndrome and Dystonia-deafness syndrome type 1 due to variants of ACTB gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2026

Related Experiment Video

Updated: May 25, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

Quantitative discrimination of NPC cell lines using optical coherence tomography.

Jianghua Li1, Changshui Chen, Bingling Chen

  • 1School for Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006, China.

Journal of Biophotonics
|February 7, 2012
PubMed
Summary

Optical coherence tomography (OCT) revealed distinct optical properties in nasopharyngeal carcinoma (NPC) cell lines, differentiating radiobiology and metastasis models. This suggests OCT

More Related Videos

Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
10:13

Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment

Published on: June 21, 2022

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Related Experiment Videos

Last Updated: May 25, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment
10:13

Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment

Published on: June 21, 2022

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Area of Science:

  • Biomedical Optics
  • Cancer Research
  • Cell Biology

Background:

  • Nasopharyngeal carcinoma (NPC) exhibits diverse biological behaviors.
  • Understanding intrinsic optical differences in NPC cell lines is crucial for diagnosis.
  • Current methods may not fully capture these cellular variations.

Purpose of the Study:

  • To investigate the intrinsic optical property differences among four representative NPC cell lines.
  • To correlate these optical properties with radiobiology and metastasis models.
  • To assess the potential of Optical Coherence Tomography (OCT) for differentiating NPC tissues.

Main Methods:

  • Utilized Optical Coherence Tomography (OCT) to analyze NPC cell line models.
  • Extracted scattering coefficients and anisotropy factors from OCT data.
  • Employed a multiple scatter effect model to fit a-scan attenuation curves.

Main Results:

  • Significant differences in scattering coefficients and anisotropy factors were observed among CNE1, CNE2, 5-8F, and 6-10B cell lines.
  • Specific values for scattering coefficients ranged from 5.21 to 6.97, and anisotropy factors from 0.86 to 0.892.
  • OCT clearly distinguished between the radiobiology and metastasis NPC cell models.

Conclusions:

  • Intrinsic optical properties vary significantly between different NPC cell lines.
  • OCT can effectively differentiate NPC cell models based on radiobiology and metastasis.
  • OCT shows potential for in vivo differentiation of NPC tissue types.