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Published on: November 2, 2012

Modeling and design by hierarchical natural moves.

Adelene Y L Sim1, Michael Levitt, Peter Minary

  • 1Department of Applied Physics, Stanford University, Stanford, CA 94305, USA.

Proceedings of the National Academy of Sciences of the United States of America
|February 7, 2012
PubMed
Summary

We developed MOSAICS (Methodologies for Optimization and Sampling in Computational Studies), a novel algorithm for nanoscale biomolecular modeling. It efficiently models large RNA structures, improving accuracy and speed over existing methods for RNA nanotechnology applications.

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