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Updated: May 25, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
[Treatment of systemic lupus erythematosus]
Alexis Mathian1, Laurent Arnaud, Zahir Amoura
1Service de médecine interne 2, Centre national de référence lupus systémique et syndrome des anticorps anti-phospholipides, hôpital La Pitiè-Salpêtrière, AP-HP, 75013 Paris.
Abstract:
Systemic lupus erythematosus is a chronic autoimmune disease. Treatment goals are to cure flares and to prevent them as well as long-term complications and drugs toxicity. Effort to improve patient knowledge and education should be a priority. SLE treatments range from long term prescription of antimalarial agents, to corticosteroids and, in severe cases, immunosuppressive agents. Patients should receive advice on environmental triggers and photoprotective measures. Other key points of the treatment include early prevention of atherosclerosis and infectious diseases. Physician must be readily available for the patient to detect flares, infections, cardiovascular events, drugs side-effects and psychiatric events. Birth control and pregnancy should be discussed early with the patient.
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